Protein Name & Synonyms:
CD178
Applications:
ELISA (dilution: 1/25, 1/50), Flow Cytometry, Immunoprecipitation
Concentration (lot specific):
IgG concentration 1.0 mg/ml
Species Reactivity:
Human
This product recognizes the human CD178 cell surface antigen, a 40kDa glycoprotein also known as Fas ligand (CD95L).
CD178 is a member of the TNF family, which is expressed by activated T lymphocytes and NK cells. The protein may exist as either a membrane bound or a cleaved soluble form.
CD178 plays an important role in T cell development and cytotoxicity. Binding of CD178 to Fas (CD95) results in the induction of apoptosis.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
This product
Spleen cells from immunised BALB/c mice were fused with cells of the P3U1 myeloma cell line.
Expiration:
12 months from the date of shipment when stored properly.