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Antigen Information
Protein Name & Synonyms:
CD227
Target Species:
- Human
Antibody Specifications
Applications:
Flow Cytometry, Immunofluorescence
Concentration:
IgG concentration 0.1 mg/ml
Species Reactivity:
Human
Specificity
Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by many epithelial tissues in vertebrates. This product recognizes CD227, also known as mucin 1 which is a breast cancer associated mucin encoded by the Muc-1 gene. CD227 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. This protein is overexpressed abundantly in >90% breast carcinomas and metastases.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Formulation:
Phosphate buffered saline
Preparation
Immunogen:
Urinary MUC-1 mucin
Preservative:
| 0.09% | Sodium Azide |
| 1% | Bovine Serum Albumin |
This product
Spleen cells from immunised Balb/c mice were fused with cells of a mouse myeloma cell line.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
