Protein Name & Synonyms:
Flow Cytometry, Immunoprecipitation
IgG concentration 1.0 mg/ml
This product is specific for the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKR2B4).
The glycoprotein CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells.
CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of 2B4 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.
Store at -20 °C.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
CD244 Fusion protein.
Spleen cells fron immunised Balb/c mice were fused with cells of the NS-1 myeloma cell line.