Protein Name & Synonyms:
CD244
Applications:
Flow Cytometry
Reconstitution:
Reconstitute with 1.0 ml distilled water
Species Reactivity:
Human
This product is specific for the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4).
The glycoprotein CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells.
CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of 2B4 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.
Prior to reconstitution store at +4 °C.
After reconstitution store at +4 °C.
DO NOT FREEZE.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Supplied as:
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized
Formulation:
Phosphate buffered saline
Reconstitution:
Reconstitute with 1.0 ml distilled water
Immunogen:
CD244 Fusion protein.
Preservative:
0.09% | Sodium Azide |
1% | Bovine Serum Albumin |
5% | Sucrose |
This product
Spleen cells from immunised Balb/c mice were fused with cells of the NS-1 myeloma cell line.