Mouse Anti-Human CD276 [+RPE]

Mouse Anti-Human CD276 [+RPE] (100 TESTS)

DS-MB-02966
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Antigen Information

Protein Name & Synonyms:
CD276
Target Species:
  • Human

Antibody Specifications

Applications:
Flow Cytometry
Reconstitution:
Reconstitute with 1.0ml distilled water
Species Reactivity:
Human

Specificity

This product detects CD276, a member of the B7 family of co-stimulatory molecules also known as B7-H3. CD276 is a type I transmembrane protein that induces the proliferation of CD4+ and CD8+ T cells, enhances the generation of cytotoxic T cells and selectively stimulates the production of interferon gamma.

Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines, and is also widely expressed in peripheral tissues including the heart, kidney, testis and colon. In humans, CD276 exists as two isoforms which result from gene duplication and differential splicing.

CD276 is reported to have therapeutic potential for the regulation of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy.

Storage/Stability

Store at +4 °C. DO NOT FREEZE.
This product should be stored undiluted. This product is photosensitive and should be protected from light.
Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized.
Formulation:
Phosphate buffered saline
Reconstitution:
Reconstitute with 1.0ml distilled water

Preparation

Preservative:
0.09%Sodium Azide (NaN3)
1%Bovine Serum Albumin
5%Sucrose

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.