Mouse Anti-Human CD55 [+RPE]

Mouse Anti-Human CD55 [+RPE] (25 TESTS/0.25ml)

$211.00
DS-MB-03139
+

Antigen Information

Protein Name & Synonyms:
CD55
Target Species:
  • Human

Antibody Specifications

Applications:
Flow Cytometry
Species Reactivity:
Human

Specificity

CD55 is the complement regulatory protein, decay accelerating factor (DAF), see Lublin D.M. & Atkinson J.P. for details. It is a 70kD glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail. In other cells the apparent molecular weight is somewhat larger. It has a substantial content of O-glycans, and also on N-glycan. DAF binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating the decay of both classical and alternative pathways. DAF carries the Cromer related blood group antigens.

DAF has a wide distribution on cells in non-hemopoietic tissues, particularly epithelium and is specifically found at the fetal-maternal interface in placenta, see Holmes C.H. et al. and Yang, P. et al. for details. Soluble forms of DAF are found, for example, in plasma, saliva and urine. The antigen on erythrocytes is pronase and chymotrypsin sensitive, but resistant to trypsin.

Storage/Stability

Store at +4 °C. DO NOT FREEZE.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 12 months after receipt.

Format

Supplied as:
Purified IgG conjugated to R. Phycoerythrin (RPE) - liquid
Formulation:
Phosphate buffered saline

Preparation

Preservative:
0.09%Sodium Azide
1%Bovine Serum Albumin
5%Sucrose

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.