Mouse Anti-Human CD58 [+APC]

Mouse Anti-Human CD58 [+APC] (100 TESTS)

$511.00
DS-MB-03145
+

Antigen Information

Protein Name & Synonyms:
CD58
Target Species:
  • Human

Antibody Specifications

Applications:
Flow Cytometry
Concentration:
IgG concentration 0.1 mg/ml
Reconstitution:
Reconstitute with 1ml distilled water
Species Reactivity:
Human

Specificity

CD58, or LFA-3, is a membrane glycoprotein of 55-70kD. It occurs in two forms, one transmembrane with a cytoplasmic domain, the other form anchored in the membrane via a glycosylphosphatidylinositol tail. The complete amino acid sequence of both forms has been deduced from cDNA. It is heavily N-glycosylated. CD58 is a cell adhesion molecule which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes[1]. It is a member of the immunoglobulin superfamily of molecules.CD58 has a wide tissue distribution, being present on erythrocytes, platelets, monocytes, a subset of lymphocytes, bone marrow cells, epithelium and endothelial cells[2]. There are approximately 5,000 CD58 molecules on each erythrocyte. There is reduced expression of CD58 on hemopoietic cells in individuals with paroxysmal nocturnal hemoglobinuria.

Storage/Stability

Prior to reconstitution store at +4 °C.
After reconstitution store at +4 °C.
DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG conjugated to Allophycocyanin (APC) - lyophilized
Formulation:
Phosphate buffered saline
Reconstitution:
Reconstitute with 1ml distilled water

Preparation

Preservative:
0.09%Sodium Azide
1%Bovine Serum Albumin

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.