Protein Name & Synonyms:
CD58
Applications:
Flow Cytometry
Concentration (lot specific):
IgG concentration 0.1 mg/ml
Reconstitution:
Reconstitute with 1ml distilled water
Species Reactivity:
Human
CD58, or LFA-3, is a membrane glycoprotein of 55-70kD. It occurs in two forms, one transmembrane with a cytoplasmic domain, the other form anchored in the membrane via a glycosylphosphatidylinositol tail. The complete amino acid sequence of both forms has been deduced from cDNA. It is heavily N-glycosylated. CD58 is a cell adhesion molecule which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes[1]. It is a member of the immunoglobulin superfamily of molecules.CD58 has a wide tissue distribution, being present on erythrocytes, platelets, monocytes, a subset of lymphocytes, bone marrow cells, epithelium and endothelial cells[2]. There are approximately 5,000 CD58 molecules on each erythrocyte. There is reduced expression of CD58 on hemopoietic cells in individuals with paroxysmal nocturnal hemoglobinuria.
Prior to reconstitution store at +4 °C.
After reconstitution store at +4 °C.
DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Supplied as:
Purified IgG conjugated to Allophycocyanin (APC) - lyophilized
Formulation:
Phosphate buffered saline
Reconstitution:
Reconstitute with 1ml distilled water
Preservative:
| 0.09% | Sodium Azide |
| 1% | Bovine Serum Albumin |
Expiration:
12 months from the date of shipment when stored properly.
