This product is specific for Cdc25A (cell division cycle 25a), a dual specificity protein phosphatase which is involved in the regulation of the cell cycle.Cdc25A is required for progression from G1 to the S phase of the cell cycle, although the protein remains active after the S phase. The activity of Cdc25A is regulated by reversible phosphorylation.Cdc25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division.Cdc25A is overexpressed by a wide variety of human cancers.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.