Mouse Anti-Human Podoplanin (D2-40)

Mouse Anti-Human D2-40

DS-MB-01143
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Antigen Information

Protein Name & Synonyms:
Podoplanin (D2-40)
Target Species:
  • Human
Immunohistology:
This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.

Specificity

This product detects podoplanin, a type-I transmembrane mucoprotein, which is highly expressed in the placenta, lung and skeletal muscle. The function of podoplanin is yet to be elucidated; however, it may be involved in cell migration and/or actin cytoskeleton organisation. It is required for normal lung cell proliferation and alveolus formation at birth, and can induce platelet aggregation.

The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor.

Podoplanin is selectively expressed in lymphangiomas, Kaposi sarcomas, and a subset of angiosarcomas with probable lymphatic differentiation.

This product is reported to be suitable for Western Blotting.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Concentrate

Preparation

Immunogen:
Resected tissue from dysgeminoma of the ovary
Preservative:
0.1%Sodium Azide (NaN3)
1%Bovine Serum Albumin

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.