Mouse Anti-Human Dectin-1 [+FITC]

Mouse Anti-Human Dectin-1 [+FITC]

129-10236
+

Antigen Information

Protein Name & Synonyms:
Dectin-1
Target Species:
  • Human

Antibody Specifications

Applications:
Flow Cytometry
Concentration:
0.1mg/ml
Host Species:
Mouse
Species Reactivity:
Human

Specificity

This product recognizes human Dectin-1, also known as beta-glucan receptor (βGR), a C-type lectin domain family member. It is a major pathogen pattern-recognition receptor that binds beta-glucans, glucose polymers that form cell-wall components or exopolymers of yeasts, fungi and some bacteria. Beta-glucans have also been used experimentally and therapeutically as immunomodulators that enhance resistance to bacterial, yeast, viral and protozoan infections, as well as tumor formation. Dectin-1 also acts as a co-stimulatory molecule on T-cells to induce their proliferation and is necessary for the TLR2-mediated inflammatory response. It is highly expressed on peripheral blood leukocytes and dendritic cells.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Formulation:
Phosphate buffered saline

Preparation

Immunogen:
NIH3T3 cells expressing full length Beta-glucan receptor.
Preservative:
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
This product
Spleen cells from immunised C57BL/6 mice were fused with cells of the murine SP2 myeloma cell line.

No posts found

Write A Review
U.S. Non-U.S.

Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.