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Antigen Information
Protein Name & Synonyms:
DR6
Target Species:
- Human
Antibody Specifications
Applications:
Flow Cytometry, Immunoprecipitation
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Human
Specificity
This product is specific for human death receptor 6 (DR6), a member of the TNFR superfamily, which possesses four extracellular cysteine-rich motifs and a cytoplasmic death domain known to signal apoptosis.
DR6 is expressed in most human tissues, including heart, placenta, pancreas, thymus, and several non-lymphoid cancer cell lines.
DR6 is involved in the proliferation and differentiation of both B and T lymphocytes.
DR6 is expressed in most human tissues, including heart, placenta, pancreas, thymus, and several non-lymphoid cancer cell lines.
DR6 is involved in the proliferation and differentiation of both B and T lymphocytes.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Fusion protein containing the extracellular region of DR6 (amino acids 42-335)
Preservative:
| 0.09% | Sodium Azide |
This product
Spleen cells from immunised F1 hybrid mice were fused with cells of the SP2/0-Ag14 myeloma cell line.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
