Protein Name & Synonyms:
ELISA, Western Blotting
IgG concentration 1.0mg/ml
This product recognizes human fibrinogen, a glycoprotein produced in the liver. Fibrinogen is a hexamer, consisting of two sets of three subunits (alpha, beta and gamma). Thrombin converts fibrinogen into fibrin, which is then cross-linked by factor XIII to form a blood clot.
This product also recognizes fibrin degradation products (FDPs), substances that are left behind after a blood clot dissolves. This process, called fibrinolysis, is produced by the action of enzymes such as plasmin on fibrin. One FDP is D-dimer, levels of which can be used to diagnose deep vein thrombosis or pulmonary embolism. The fibrinolytic system is also closely linked to the control of inflammation.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
Fibrin degradation products
0.09% Sodium Azide (NaN3)
Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line.