Protein Name & Synonyms:
Immunohistology - Paraffin, Western Blotting
IgG concentration 1.0 mg/ml
This product recognizes Granzyme A, a 60kD disulphide-linked homodimeric protein expressed in cytoplasmic granules of cytotoxic lymphocytes.
The biological function of Granzyme A is unclear. It would appear that the molecule may have a role in the induction of apoptosis via its activity as a serine protease, but this would seem to be subsidiary to the role of Granzyme B. Granzyme A deficient mice are indistinguishable from normal animals in their response to infection.
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline.
Recombinant human Granzyme A
0.09% Sodium Azide (NaN3)
Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.