Protein Name & Synonyms:
Immunohistology - Frozen, ELISA (dilution: 1/10 , 1/100), Flow Cytometry, Immunofluorescence, Immunoprecipitation
IgG concentration 1.0 mg/ml
Human, rhesus monkey, chimpanzee
This product recognizes the serine protease Granzyme B, which is important in the induction of apoptosis in target cells by cytolytic lymphocytes (CTLs).
Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell, Granzyme B activates the cascade of caspases that finally results in cell death.
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Tris buffered saline
Purified human Granzyme B
Spleen cells from immunised Balb/c mice were fused with cells of the mouse SP2/0 myeloma cell line.