Protein Name & Synonyms:
ELISA (dilution: 0.5, 1.0ug/ml), Western Blotting
IgG concentration 1.0mg/ml
This product detects a band of approximately 24kDa in HeLa, K567 and RAJI whole cell lysates under reducing conditions.
This product specifically recognizes human H-Ras, otherwise known as p21Ras, a ubiquitously expressed lipid-anchored GTPase and member of the Ras superfamily of small GTPases, which acts as a molecular signal transduction on/off switch on the inner surface of the plasma membrane and endomembranes.
H-Ras, N-Ras and K-Ras4A/4B are highly related RAS genes which regulate pathways involved in cell differentiation, proliferation, adhesion, migration and apoptosis and are known proto-oncogenes. Mutations in the H-Ras gene are responsible for the rare condition known as Costello syndrome characterized by facial, cardiovascular and musculoskeletal abnormalities and mental retardation.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
Synthetic peptide corresponding to amino acids DIHQYREQIKRVKDSDDC of human H-Ras.
0.09% Sodium Azide (NaN3)