Mouse Anti-Human HLA ABC

Mouse Anti-Human HLA ABC

$715.00
DS-MB-01540
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Antigen Information

Protein Name & Synonyms:
HLA ABC
Target Species:
  • Human

Antibody Specifications

Applications:
Immunohistology - Frozen, ELISA (dilution: 1/50 , 1/100), Flow Cytometry, Functional Assays, Immunofluorescence, Immunoprecipitation
Concentration:
IgG concentration 1.0 mg/ml
Species Reactivity:
Human, Rhesus macaque, bovine, Cynomolgus monkey and baboon

Specificity

The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C. These proteins are found on the surface of almost all nucleated somatic cells.

This product recognizes an antigenic determinant shared among products of the HLA A, B and C loci. This antibody recognizes a conformational epitope, reacting with HLA class I alpha3 and alpha2 domains, see Ishitani, A. et al. for details.

This product is routinely tested in flow cytometry on human peripheral blood lymphocytes.

Storage/Stability

Store at -20 °C only

This product should be stored undiluted.

Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Quality Control (Contaminants):
<0.01 EU/ug
Format Type:
Low Endotoxin

Preparation

Immunogen:
Purified human tonsil lymphocyte membranes.
Preservative:
None present
This product
Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1/1-Ag4.1 myeloma cell line.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.