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Antigen Information
Protein Name & Synonyms:
HLA ABC
Target Species:
- Human
Antibody Specifications
Applications:
Flow Cytometry
Concentration:
IgG concentration 0.1 mg/ml
Species Reactivity:
Human, Rhesus macaque, bovine, Cynomolgus monkey and baboon
Specificity
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C. These proteins are found on the surface of almost all nucleated somatic cells.
This product recognizes an antigenic determinant shared among products of the HLA A, B and C loci. This antibody recognizes a conformational epitope, reacting with HLA class I alpha3 and alpha2 domains, see Ishitani, A. et al. for details.
This product is routinely tested in flow cytometry on human peripheral blood lymphocytes.
This product recognizes an antigenic determinant shared among products of the HLA A, B and C loci. This antibody recognizes a conformational epitope, reacting with HLA class I alpha3 and alpha2 domains, see Ishitani, A. et al. for details.
This product is routinely tested in flow cytometry on human peripheral blood lymphocytes.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Formulation:
Phosphate buffered saline
Preparation
Immunogen:
Purified human tonsil lymphocyte membranes.
Preservative:
| 0.09% | Sodium Azide |
| 1% | Bovine Serum Albumin |
This product
Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSI/I-Ag4.1 myeloma cell line
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
