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Product Specifications

Size:

0.1 mg

Protein Information

Protein Name & Synonyms:

HLA ABC

Target Species:

Human

Antibody Specifications

Applications:

Flow Cytometry

Concentration (lot specific):

IgG concentration 0.1 mg/ml

Species Reactivity:

Human, Rhesus macaque, bovine, Cynomolgus monkey and baboon

Specificity

The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C. These proteins are found on the surface of almost all nucleated somatic cells.

This product recognizes an antigenic determinant shared among products of the HLA A, B and C loci. This antibody recognizes a conformational epitope, reacting with HLA class I alpha3 and alpha2 domains, see Ishitani, A. et al. for details.

This product is routinely tested in flow cytometry on human peripheral blood lymphocytes.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:

Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid

Formulation:

Phosphate buffered saline

Preparation

Immunogen:

Purified human tonsil lymphocyte membranes.

Preservative:

0.09%	Sodium Azide
1%	Bovine Serum Albumin

This product

Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSI/I-Ag4.1 myeloma cell line

Expiration:

12 months from the date of shipment when stored properly.