Protein Name & Synonyms:
HLA ABC
Applications:
Immunohistology - Frozen
Concentration (lot specific):
IgG concentration 1.0 mg/ml
Species Reactivity:
Human, This antibody is reported to cross react with Rhesus macaque, bovine, Cynomolgus monkey and baboon
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C. These proteins are found on the surface of almost all nucleated somatic cells.
This product recognizes an antigenic determinant shared among products of the HLA A, B and C loci. This antibody recognizes a conformational epitope, reacting with HLA class I alpha3 and alpha2 domains, see Ishitani, A. et al. for details.
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Supplied as:
Purified IgG conjugated to Horseradish Peroxidase (HRP) - liquid
Formulation:
Phosphate buffered saline
Immunogen:
Purified human tonsil lymphocyte membranes.
This product
Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1/1-Ag4.1 myeloma cell line.
Expiration:
12 months from the date of shipment when stored properly.