Protein Name & Synonyms:
HLA B7
Applications:
Flow Cytometry
Concentration (lot specific):
IgG concentration 1.0 mg/ml
Species Reactivity:
Human, This antibody is reported to cross react with Cynomolgus monkey
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C.
The HLA B gene is part of the human HLA complex on chromosome 6 and there are a large number of variant alleles of this gene. This product recognizes the HLA B7 antigen and does not cross-react with HLA B27 or other related antigens. It can be used to distinguish true HLA B27 positives from false HLA B27 positives (i.e. HLA B7 positive) in the investigation of diseases such as ankylosing spondylitis and anterior uveitis.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Immunogen:
Papain solubilized HLA-B7 antigen
Expiration:
12 months from the date of shipment when stored properly.