Mouse Anti-Human Mesothelin

Mouse Anti-Human Mesothelin

$1,319.00
DS-MB-01886
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Antigen Information

Protein Name & Synonyms:
Mesothelin
Target Species:
  • Human

Antibody Specifications

Applications:
Immunohistology - Frozen
Species Reactivity:
Human, Cynomolgus monkey

Specificity

This product binds Mesothelin, a 40kDa GPI-anchored cell surface glycoprotein. Mesothelin is a differentiation antigen present on normal mesothelial cells and overexpressed in several human tumors, including mesothelioma; ovarian and pancreatic adenocarcinoma. Mesothelin is attached to the cell membrane by a glycosylphosphatidyl inositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). The biological function of mesothelin is not known.

The K1 antibody has been used to differentiate between epithelial malignant mesothelioma and lung adenocarcinomas by immunohistology.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Ascitic Fluid - Diluted
Formulation:
Phosphate buffered saline
Format Type:
Concentrate

Preparation

Immunogen:
Spleen lymphocytes from mice fused with ovcar-3
Preservative:
0.09%Sodium Azide (NaN3)
1%Bovine Serum Albumin

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.