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Antigen Information
Protein Name & Synonyms:
PDGF R beta / CD140b
Target Species:
- Human
Antibody Specifications
Applications:
Immunohistology - Frozen, Flow Cytometry, Immunofluorescence, Immunoprecipitation, Immunohistology - Paraffin, Western Blotting
Concentration:
1.0 mg/ml
Species Reactivity:
Human, Baboon, Monkey
Specificity
This product is specific for the extracellular domain of the human PDGF receptor beta subunit. This was confirmed in binding studies using several different cell lines and by its ability to immunoprecipitate PDGF receptor beta complexed with 125I-PDGF-BB. This product does not recognize PDGF receptor alpha.PDGF receptor beta is a member of the class III receptor tyrosine kinase family that also includes M-CSF receptor, SCF receptor and Flt-3. Binding of PDGF-BB induces receptor homodimerization or heterodimerization with PDGF receptor alpha.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Human skin fibroblast cell membrane extracts
Preservative:
| 0.09% | Sodium Azide (NaN3) |
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
