Cart Is Empty
770-729-2992
Please login to download this attachment
Product Specifications
Size:
0.1 mg
Protein Information
Protein Name & Synonyms:
SLP-76
Target Species:
- Human
Antibody Specifications
Applications:
Immunoprecipitation, Western Blotting
Concentration (lot specific):
Ig concentration 1.0 mg/ml
Species Reactivity:
Human, Mouse, Porcine
This product detects a band of approximately 76kDa in T lymphocyte cell lysates.
Specificity
This product recognizes the SH2 domain-containing leucocyte protein (SLP-76), a 76kDa tyrosine phosphoprotein, expressed primarily by T lymphocytes and cells of the myeloid lineage.
SLP-76 is one of several adaptor proteins assisting with TCR-mediated signal transduction, through GRB2 binding, functioning as a substrate for the protein-tyrosine kinase ZAP-70 and thus playing a crucial role in both T cell ontogeny and activation. Other molecules that associate with SLP-76 include phospholipase C (PLC)❏❏gamma, Vav, Nck and fyn binding protein.
SLP-76 is one of several adaptor proteins assisting with TCR-mediated signal transduction, through GRB2 binding, functioning as a substrate for the protein-tyrosine kinase ZAP-70 and thus playing a crucial role in both T cell ontogeny and activation. Other molecules that associate with SLP-76 include phospholipase C (PLC)❏❏gamma, Vav, Nck and fyn binding protein.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
A fusion protein corresponding to amino acids 216-434 of human SLP-76
Preservative:
| 0.09% | Sodium Azide |
Expiration:
12 months from the date of shipment when stored properly.
No posts found
Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
