Mouse Anti-Human SYK

Mouse Anti-Human SYK


Product Specifications

0.1 mg

Protein Information

Protein Name & Synonyms:
Target Species:
  • Human

Antibody Specifications

Immunoprecipitation, Western Blotting
Concentration (lot specific):
Ig concentration 1.0 mg/ml
Species Reactivity:
Human, mouse and rat

This product detects a band of approximately 72kDa in Ramos & RBL cell lysates.


This product recognizes protein tyrosine kinase p72syk (syk), a 72kDa non-receptor tyrosine kinase, critical for immunoreceptor signaling in hematopoietic cells, but also expressed by nonhematopoietic cells, including fibroblasts, endothelial cells and hepatocytes.

Syk plays an important role in mast cell response, initiated by the aggregation of the IgE high affinity receptor Fc epsilon R1. Phosphorylation of ITAMs within Fc receptor R1 by another tyrosine kinase lyn, results in the recruitment of syk, which is then responsible for the further phosphorylation of numerous target proteins within many different signal transduction pathways.

Further studies have shown that syk also plays a major role in B cell receptor-mediated apoptosis, proliferation and hematopoiesis. Syk is also reported to associate with protein kinase C alpha during platelet activation.


Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody.
If stored in this manner, this product is stable for 18 months after receipt.


Supplied as:
Purified IgG - liquid
Phosphate buffered saline
Format Type:


Recombinant fragment corresponding to amino acids 5 - 360 of human syk.
0.09%Sodium Azide
12 months from the date of shipment when stored properly.

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This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.