Mouse Anti-Human TREM-1 [+RPE]

Mouse Anti-Human TREM-1 [+RPE]

129-10656
+

Antigen Information

Protein Name & Synonyms:
TREM-1
Target Species:
  • Human

Antibody Specifications

Applications:
Flow Cytometry
Host Species:
Mouse
Species Reactivity:
Human

Specificity

This product recognizes Triggering receptor expressed on myeloid cells 1 (TREM-1), a receptor expressed on CD14+ monocytes, macrophages and neutrophils. It is also highly expressed in inflammatory lesions caused by fungi and bacteria. It stimulates neutrophils and monocytes-mediated inflammatory responses. TREM-1 activation, together with LPS and other PRR ligands, amplifies the production pro-inflammatory cytokines and thus the inflammatory response. The TREM-1 pathway also plays a crucial role in septic shock.

This product has been shown to activate monocytes and granulocytes.

Storage/Stability

Store at +4 °C. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use. This product is photosensitive and should be protected from light.
If stored in this manner, this product is stable for 12 months after receipt.

Format

Supplied as:
Purified IgG conjugated to R. Phycoerythrin (RPE) - liquid
Formulation:
Phosphate buffered saline

Preparation

Immunogen:
Recombinant human TREM-1
Preservative:
0.09% Sodium Azide (NaN3)
0.2% Bovine Serum Albumin

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.