Protein Name & Synonyms:
ELISA (dilution: 5ug/ml, 10ug/ml), Flow Cytometry, Immunoprecipitation, Immunohistology - Paraffin, Western Blotting
IgG concentration 1.0 mg/ml
The thyroid stimulating hormone (TSH) receptor (otherwise known as the thyrotropin receptor) is an important molecule in controlling the growth and function of the normal thyroid.
The antibody recognizes both native and denatured TSH receptor (binding to an epitope at the carboxy terminus between amino acids 354 and 359). It does inhibit binding of TSH. No cross reactivity has been observed with related LH and FSH receptors.
This antibody recognizes the mutant TSH receptor known as I167N as well as the wild type molecule.
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
Recombinant Human TSH receptor
Spleen cells from immunised BALB/c mice were fused with cells of the NS1/Ag4.1 mouse myeloma cell line.