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Antigen Information

Protein Name & Synonyms:

Vitronectin

Target Species:

Human

Antibody Specifications

Applications:

Immunohistology - Frozen, ELISA (dilution: 5 ug/ml, 20 ug/ml), Western Blotting

Concentration:

1.0 mg/ml

Species Reactivity:

Human

Specificity

This product is specific for vitronectin and will react with the native and denatured forms. It does not cross react with fibronectin.

Vitronectin is one of the 2 most important cell adhesive proteins found in the blood and extracellular matrix. It exists as a mixture of 2 monomeric glycoproteins that mediate cell adhesion through an interaction between the R-G-D sequence, present in the cell binding domains, and several different integrin receptors. It is also known as a complement lysis inhibitor and as a scavenger protein for macromolecular products of the complement and homeostasis cascades.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:

Purified IgG - liquid

Formulation:

Phosphate buffered saline

Format Type:

Purified

Preparation

Immunogen:

Purified vitronectin from human plasma

Preservative:

0.09%