Protein Name & Synonyms:
ZAP70
Applications:
Flow Cytometry
Concentration (lot specific):
IgG concentration 0.1 mg/ml
Species Reactivity:
Human
This product recognizes human ZAP-70, a 70kDa tyrosine protein kinase which associates with the T-cell receptor (TCR) zeta chain and undergoes phosphorylation following TCR stimulation. ZAP-70 is primarily expressed in T lymphocytes and natural killer cells, where it plays a key role in T-cell receptor (TCR) signalling. Recent studies suggest that ZAP-70 is also expressed in a population of normal immature B-cells and in B-cells from a sub-set of patients with chronic lymphocytic leukaemia.
Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. This product should be stored undiluted.
This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Supplied as:
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Formulation:
Phosphate buffered saline
Immunogen:
Peptide corresponding to amino acid residues 280-309 of human ZAP-70, conjugated to KLH.
Preservative:
0.1% Sodium Azide (NaN3)
Expiration:
12 months from the date of shipment when stored properly.