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Antigen Information
Protein Name & Synonyms:
MHC Class I
Target Species:
- Mouse
Antibody Specifications
Applications:
Flow Cytometry
Concentration:
IgG concentration 0.1 mg/ml
Species Reactivity:
Mouse, Sheep, dog, pig, cow, guinea pig and rat
Specificity
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the histocompatibility 2 (H-2) region.
This product recognizes a monomorphic epitope present on murine MHC class I molecules, which are expressed at varying levels on the majority of nucleated cells. The epitope recognized by This product is conformation dependent and is reported to be phylogenetically conserved.
Reactivity has been observed with some canine samples suggesting that this antibody may recognize a polymorphic epitope of canine MHC class I.
This product recognizes a monomorphic epitope present on murine MHC class I molecules, which are expressed at varying levels on the majority of nucleated cells. The epitope recognized by This product is conformation dependent and is reported to be phylogenetically conserved.
Reactivity has been observed with some canine samples suggesting that this antibody may recognize a polymorphic epitope of canine MHC class I.
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Formulation:
Phosphate buffered saline
Preparation
Immunogen:
Purified H-2Kb and H-2Db MHC I molecules.
Preservative:
| 0.09% | Sodium Azide |
| 1% | Bovine Serum Albumin |
This product
Spleen cells from immunised C1D mice were fused with cells of the X63 myeloma cell line.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
