Protein Name & Synonyms:
MHC Class I
Flow Cytometry, Immunoprecipitation
IgG concentration 1.0 mg/ml
Mouse, Sheep, dog, pig, cow, guinea pig and rat
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the histocompatibility 2 (H-2) region.
This product recognizes a monomorphic epitope present on murine MHC class I molecules, which are expressed at varying levels on the majority of nucleated cells. The epitope recognized by This product is conformation dependent and is reported to be phylogenetically conserved.
Reactivity has been observed with some canine samples suggesting that this antibody may recognize a polymorphic epitope of canine MHC class I.
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Purified IgG - liquid
Phosphate buffered saline
Purified H-2Kb and H-2Db MHC I molecules.
Spleen cells from immunised C1D mice were fused with cells of the X63 myeloma cell line.