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770-729-2992
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Product Specifications
Size:
0.1 mg
Protein Information
Protein Name & Synonyms:
Tubulin beta
Target Species:
- Porcine (pig)
Antibody Specifications
Applications:
Immunohistology - Frozen, ELISA (dilution: , 1.0ug/ml), Western Blotting
Concentration (lot specific):
IgG concentration 1.0mg/ml
Species Reactivity:
Pig, Human, Mouse, Plants, Rat
This product detects a band of approximately 50kDa in human RAJI and mouse EL4 cell lysates.
Specificity
This product recognizes an epitope within the N-terminal region (NT) of tubulin beta, a 50kDa globular protein and major constituent of microtubules within the cytoskeleton, involved in meiosis, mitosis, intracellular transport and maintaining cell shape.
The evolutionarily conserved heterodimer tubulin, made up of a tubulin alpha and beta chain, binds two molecules of GTP, one at a non-exchangeable site on the alpha chain and one at an exchangeable site on the beta chain. Only the beta chain possesses GTPase activity however, hydrolysing GTP to GDP, and influencing the stability of the dimer within the microtubule.
This product is reported to partially inhibit microtubule assembly in vitro, see Draber, P. et al. for details. This product is reported as suitable for use in immunocytochemistry.
The evolutionarily conserved heterodimer tubulin, made up of a tubulin alpha and beta chain, binds two molecules of GTP, one at a non-exchangeable site on the alpha chain and one at an exchangeable site on the beta chain. Only the beta chain possesses GTPase activity however, hydrolysing GTP to GDP, and influencing the stability of the dimer within the microtubule.
This product is reported to partially inhibit microtubule assembly in vitro, see Draber, P. et al. for details. This product is reported as suitable for use in immunocytochemistry.
Storage/Stability
Store at +4 °C. DO NOT FREEZE.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgM - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Tubulin beta from porcine brain.
Preservative:
| 0.09% | Sodium Azide (NaN3) |
Expiration:
12 months from the date of shipment when stored properly.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
