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Antigen Information

Protein Name & Synonyms:

MHC Class II I-Ak,s

Target Species:

Antibody Specifications

Applications:

Immunohistology - Frozen, Flow Cytometry, Immunohistology - Paraffin

Concentration:

IgG concentration 1.0 mg/ml

Species Reactivity:

Rat, Mouse haplotypes k and s Does not recognize BDIX rat strain

Specificity

The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the H-2 region. In rats, this complex is referred to as the RT1 region.

This product recognizes a monomorphic determinant of the rat RT1B MHC class II antigen present on B lymphocytes, dendritic cells, some macrophages and certain epithelial cells.

The literature reports that this antibody reacts with a polymorphic determinant on mouse strains of the H-2 haplotypes k and s. Analysis of recombinant mouse strains has mapped the OX-6 determinant to the H-2I-A region. for details.

This product is routinely tested in flow cytometry on rat splenocytes.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:

Purified IgG - liquid

Formulation:

Phosphate buffered saline

Format Type:

Purified

Preparation

Immunogen:

Rat thymocyte membrane glycoprotein

Preservative:

0.09%

Sodium Azide

This product