Mouse Anti-Staph. aureus Enterotoxin A

This product recognizes Staphylococcus aureus enterotoxin type A. Staphylococcus aureus produces several different types of enterotoxins (SE❏'s). The SE❏'s are short, soluble proteins that are highly stable and resistant to most proteolytic enzymes. They belong to a family of pyrogenic toxins and as such cause an increase in body temperature, immunosuppression and non-specific T-cell proliferation. These activities are referred to as superantigen activity and results from the interaction of SE❏'s with T-cell antigen receptors and the major histocompatibility complex (MHC) on antigen presenting cells. In addition to their superantigen activity, SE❏'s are also emetics (they cause vomiting). The SE❏'s are important in food poisoning. Enterotoxin A is one of the SE❏'s most commonly identified in clinical isolates.