Mouse Anti-Vaccinia Virus

Mouse Anti-Vaccinia Virus

DS-MB-03560
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Antigen Information

Protein Name & Synonyms:
Vaccinia Virus
Target Species:
  • Viral

Antibody Specifications

Applications:
ELISA, Western Blotting
Concentration:
IgG concentration 1.0mg/ml
Species Reactivity:
Viral

This product detects a band of approximately 27kDa under non-reducing conditions.

Specificity

This product recognizes the Vaccinia virus, a large poxvirus. Poxviruses are DNA viruses that replicate in the cytoplasm of the host cell and therefore need a large genome to encode for the various proteins involved in DNA replication and transcription. Vaccinia virus infection is very mild and generally causes no symptoms in healthy individuals. Vaccinia infection initiates immune responses that also protects against smallpox, a much more severe disease with a high mortality rate. Vaccinia is best known for its use as a vaccine against smallpox, which was officially declared eradicated in 1980. There is some concern that smallpox might be re-introduced as a biological weapon, as such it might still pose a threat to humanity.

This product recognizes a 27kDa protein in Western blotting of the following viruses: Vaccinia virus strain Elstree, Ectromelia virus strain K-1, Cowpox virus strain Grishak. It might also recognize the same protein in the Smallpox virus.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.

This product should be stored undiluted.

Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified

Preparation

Immunogen:
Live dry smallpox vaccine
Preservative:
0.09% Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.