Multiomics Services

What is Multiomics?

Multiomics (multiple omics) integrates multiple levels of biological analysis to provide an integrated, comprehensive view of complex cellular systems. This approach can offer avenues into discovery and changes in normal development, cell and tissue level responses, and disease states. The traditional approach combines genomic data with data from other modalities such as proteomics, transcriptomics, and epigenetics, to measure gene expression, gene activation, and protein levels and post-translational modifications. Using several omics technologies together, researchers can better connect singular datasets to whole cell or organism phenotypes and to identify novel drug targets and biomarkers.

The Goals of Multiomics

Technological advancements in genomic sequencing and proteomic analyses is not only improving sensitivity, specificity, throughput, and resolution (down to the single cell level) but also minimizing labor, time, and sample volume requirements. This allows what was previously considered impossible to be possible. Multiomics-based integration of multiple methods as a source of high-throughput data provides a comprehensive dataset of research aims and discovery science as a whole.

Our Solutions

RayBiotech's unmatched array technology and expertise makes it possible to identify, track, and map protein expression, phosphorylation, and glycosylation of 1000 analytes across hundreds of biochemical pathways. Our wide portfolio of proteomic solutions fits the discovery needs of both small and large projects. By combining our 2-dimensional, individual technologies into a 3-dimensional perspective of your research, we can produce a multiomic insight into health and disease.

Send Us Your Samples, We'll Send You Results

Ship us your samples (4 sample minimum) and our experienced service team will use our GLP-compliant laboratory, automated slide processing system and careful, thorough data analysis to ensure the most efficient, high-quality, reproducible results available anywhere. Fill out the web-based quote request form to get a formal quote emailed to you within 24 hours. If you are ready to ship the samples, fill out the service form and follow the sample shipment instructions linked below.

Label-Based Platform

Through a simple labeling process, the sample proteins are directly conjugated to biotin, eliminating the need for a second antibody to develop the array signals. Proteins binding to the array are detected a streptavidin-conjugated fluor. In this format, unintended antibody interactions are impossible, thus eliminating limitations on the size of the array panel.

Sandwich-Based Platform

These arrays utilize the sandwich-ELISA design principle. Where, capture antibodies are printed in multiple identical arrays on a standard-sized histology slide. After a blocking step, samples are incubated with the arrays. Nonspecific proteins are then washed off, and the arrays are incubated with a cocktail of biotinylated detection antibodies, followed by a streptavidin-conjugated fluor.

1000 Protein Expression

Number of Targets
1,000

Design Principle
Label-based

Sample Types
Serum, plasma, cell culture media

Sample Volume Needed
40 ul (500 ul for cell culture media)

Kit Used
Human L1000 Array, Glass Slide

1000 Protein Glycosylation

Number of Targets
1,000

Design Principle
Sandwich-based

Sample Types
Serum, plasma, lysates, cell culture media

Sample Volume Needed
20 ul (800 ul for cell culture media)

Kit Used
Human Glycosylation Array 1000

1000 Protein Phosphorylation

Number of Targets
1,000

Design Principle
Sandwich-based

Sample Types
Serum, plasma, lysates, cell culture media

Sample Volume Needed
1.5 ml (3 ml for cell culture media)
Low volume options available

Kit Used
Human Tyrosine Phosphorylation Array G1000

507 Protein Expression

Number of Targets
507

Design Principle
Label-based

Sample Types
Serum, plasma, cell culture media

Sample Volume Needed
40 ul (500 ul for cell culture media)

Kit Used
Human L507 Array, Glass Slide

507 Protein Glycosylation

Number of Targets
507

Design Principle
Sandwich-based

Sample Types
Serum, plasma, lysates, cell culture media

Sample Volume Needed
20 ul (800 ul for cell culture media)

Kit Used
Human Glycosylation Array 507

507 Protein Phosphorylation

Number of Targets
507

Design Principle
Sandwich-based

Sample Types
Serum, plasma, lysates, cell culture media

Sample Volume Needed
1.5 ml (3 ml for cell culture media)
Low volume options available

Kit Used
Human Tyrosine Phosphorylation Array G1

Biostatistics & Bioinformatics Analysis Service

Multiomics venn diagram
Distribution of differentially-expressed targets on 3 multiomic arrays
GO molecular function graph
GO molecular function over-representation analysis with 8 differentially expressed biomarkers targets differentially-expression in all 3 arrays

Features

  • Differential Expression analysis: Statistical analysis identifies the proteins that are statistically significant between different groups of samples
  • Pathway analysis: Pathway analysis identifies the specific protein functions, biological pathways, and physical interactions that are enriched in a particular group.

Our Differentiators

Expertise

Cited in more than 8,000 peer-reviews publications, our proven technology has enabled thousands of researchers to make novel discoveries that help advance scientific research globally

High quality data

Our cutting-edge technologies provides high sensitivity and specificity across platforms

Fast turnaround time

On average 2-3 weeks from receipt

Powerful partnership

We are a CRO that offers collaboration and customization to generate unique, tailored solutions for successful outcomes