N/A Anti-14-3-3, multiple isoforms

N/A Anti-14-3-3, multiple isoforms

$853.00
DS-PB-02380
+

Antigen Information

Protein Name & Synonyms:
14-3-3, multiple isoforms
Target Species:
  • Sheep

Antibody Specifications

Applications:
ELISA, Immunohistology - Paraffin, Western Blotting
Preparation:
Antisera to the relevant sheep 14-3-3 isoform were raised by repeated immunisations of rabbits with highly purified antigen.
Species Reactivity:
Sheep

All This product component parts detect a band of approximately 30kDa in HEK293 cell lysates.

Specificity

This product provides the user with a sample panel of the 7 mammalian isoforms of 14-3-3 protein, each component part recognising the acetylated N-terminal region of the relevant isoform. Note: may not react with recombinant proteins that are not N-acetylated.

14-3-3 is a member of the 14-3-3 family, consisting of acidic 30kDa proteins involved in multiple protein kinase signalling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3, show distinct preferences for the different isoforms, and are regulated by phosphorylation of both 14-3-3 and the bound protein.

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:
Serum - liquid
Format Type:
Serum

Preparation

Antisera to the relevant sheep 14-3-3 isoform were raised by repeated immunisations of rabbits with highly purified antigen.

Immunogen:
Synthetic peptide corresponding to acetylated N-terminal sequence of sheep 14-3-3 beta, epsilon, eta, gamma, sigma, tau/theta, zeta accordingly.
Preservative:
0.09%Sodium Azide (NaN3)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.