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Native Human C3b

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DS-01-0502
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Source

Species:
Human
Protein Name & Synonyms:
C3b,

Preparation

Purity:
>90% by SDS-PAGE
Molecular Weight (kDa):
180kDa

Protein Specifications

Format:
Purified C3b from human serum - liquid
Concentration:
~1.0 mg/ml
Preservative:
None present
Recommended Applications:
ELISA

Description

Cleavage of the C3-alpha chain at peptide bond 77 results in production of C3a and C3b fragments. The C3b fragment is a glycoprotein composed of the modified C3-alpha chain and the intact C3-beta chain. Nascent C3b has the transient ability to form a covalent ester bond with a variety of target surfaces. Once bound to target surfaces C3b becomes an essential subunit of both the classical and alternative pathway C5 cleaving enzymes.

Specifications

Size
100 ug
Assay Buffers
Phosphate buffered saline

Stability & Storage

Storage/Stability
Store at -20°C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for12 months from date of dispatch.

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.