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Source
Species:
Human
Protein Name & Synonyms:
C3b,
Preparation
Purity:
>90% by SDS-PAGE
Molecular Weight (kDa):
180kDa
Protein Specifications
Format:
Purified C3b from human serum - liquid
Concentration:
~1.0 mg/ml
Preservative:
None present
Recommended Applications:
ELISA
Description
Cleavage of the C3-alpha chain at peptide bond 77 results in production of C3a and C3b fragments. The C3b fragment is a glycoprotein composed of the modified C3-alpha chain and the intact C3-beta chain. Nascent C3b has the transient ability to form a covalent ester bond with a variety of target surfaces. Once bound to target surfaces C3b becomes an essential subunit of both the classical and alternative pathway C5 cleaving enzymes.
Specifications
Size
100 ug
Assay Buffers
Phosphate buffered saline
Stability & Storage
Storage/Stability
Store at -20°C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for12 months from date of dispatch.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use. This protein may be stored for12 months from date of dispatch.
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Usage
This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.
