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Obesity Arrays
Obesity and the diseases arising from it (diabetes, cardiovascular disease and cancer) constitute a major health challenge to the industrialized world. In the past decade, it has become apparent that adipose tissue is not an inert fat-storage depot, but a major endocrine organ which secretes numerous soluble factors and regulates many processes related to glucose homeostasis, lipid and protein metabolism, hunger/satiety, inflammatory and immune responses, and vascular function. Collectively, these factors are referred to as adipokines. Some are mainly produced by adipose tissue (e.g., leptin and resistin), while others are classical cytokines such as TNF-α, IL-6, MCP-1, and IL-1, which are also synthesized in other tissues. Understanding adipokine-mediated molecular signaling is critical to understanding and treating the myriad of diseases resulting from obesity.
RayBiotech offers 5 different Obesity Antibody Arrays for detecting up to 62 Adipokines. See the below product listings for more information.
Human Obesity Arrays
Human Obesity Array Q1
(QAH-ADI-1)Quantibody Arrays - Quantitative, Sandwich-Based, Glass Slide Antibody Arrays
Detects 10 Human Adipokines:
IGF-1, IL-1 beta (IL-1 F2), IL-6, IL-8 (CXCL8), Insulin, Leptin, MCP-1 (CCL2), PAI-1, Resistin, TNF alpha
Human Obesity Array Q3
(QAH-ADI-3)Quantibody Arrays - Quantitative, Sandwich-Based, Glass Slide Antibody Arrays
Detects 40 Human Adipokines:
Adiponectin (ACRP30), Adipsin (Complement Factor D), AgRP, ANGPTL4, BDNF, Chemerin, CRP (C-Reactive Protein), Growth Hormone, IFN-gamma, IGFBP-1, IGFBP-2, IGF-1, IL-10, IL-12 p40, IL-12 p70, IL-1 beta (IL-1 F2), IL-1 ra (IL-1 F3), IL-6, IL-8 (CXCL8), Insulin, Leptin, Lipocalin-2 (NGAL), MSP alpha/beta, Osteoprotegerin (TNFRSF11B), PAI-1, PDGF-BB, Pepsinogen 1, Pepsinogen 2, Procalcitonin, Prolactin, RANTES (CCL5), RBP4, Resistin, SAA (Serum Amyloid A), TGF beta 1, Thrombospondin 1, TNF RI (TNFRSF1A), TNF RII (TNFRSF1B), TNF alpha, VEGF-A
Human L182 Array, Membrane
(AAH-BLM-ADI-1)L-Series Arrays - Semi-quantitative, label-Based, high density antibody arrays
Detects 182 Human Adipokines:
ACE / CD43, ACE-2, ACTH, ADFP, Adiponectin, Adipsin (Factor D), AgRP , AMPKa1 , Amylin, Angiopoietin 1, Angiopoietin 2, Angiotensinogen / Angiotensin II, Ang-like Factor, ANGPTL1, ANGPTL2, ANGPTL3, ANGPTL4 , Apelin Receptor , ApoB, ApoE, Axl, BDNF, bFGF, BMP-2 , BMP-3, BMP-3b / GDF-10, BMP-4 , BMP-5, BMP-6, BMP-7, BMP-8, BMP-15, BMPR-IA / ALK-3, BMPR-IB / ALK-6, BMPR-II, b-NGF, C3a des Arg, CART , CD137 (4-1BB), CD36, Clusterin, CNTF, C-peptide, CRP , Cystatin C, Dtk, EGF, EGFR, ENA-78, Endophin Beta, Epiregulin, E-selectin, ET-1 (Endothelin), FABP4, FAM3B, FAS / Apo-1, FGF-10, FGF-6, FSH , Galectin -1, Growth Hormone (Growth Hormone), Ghrelin, GITR, GITR Ligand, GLP-1 , Glucagon, Glut1, Glut2, Glut3, Glut5, Glutathione peroxidase 1, Glutathione peroxidase 3, GRO alpha, HCC4, HGF, HSD-1, ICAM1, IFN-gamma, IGF-1, ...View all 182 human adipokine proteins
Human Obesity Array C1
(AAH-ADI-1)C-Series Arrays - Semi-Quantitative, Sandwich-Based, Membrane Antibody Arrays
Detects 62 Human Adipokines:
4-1BB (TNFRSF9/CD137), ACE-2, Adiponectin (ACRP30), Adipsin (Complement Factor D), AgRP, Angiopoietin-1, Angiopoietin-2, ANGPTL4, CRP (C-Reactive Protein), ENA-78 (CXCL5), Fas (TNFRSF6/Apo-1), FGF-6, Growth Hormone, HCC-4 (CCL16), IFN-gamma, IGFBP-1, IGFBP-2, IGFBP-3, IGF-1, IGF-1 R, IL-1 R4 (ST2), IL-1 R1, IL-10, IL-11, IL-12 p70, IL-1 alpha (IL-1 F1), IL-1 beta (IL-1 F2), IL-6, IL-6 R, IL-8 (CXCL8), Insulin, IP-10 (CXCL10), Leptin R, Leptin, LIF, Lymphotactin (XCL1), MCP-1 (CCL2), MCP-3 (MARC/CCL7), M-CSF, MIF, MIP-1 beta (CCL4), MSP alpha/beta, Osteoprotegerin (TNFRSF11B), Oncostatin M, PAI-1, PARC (CCL18), PDGF-AA, PDGF-AB, PDGF-BB, RANTES (CCL5), Resistin, SAA (Serum Amyloid A), SDF-1 alpha (CXCL12 alpha), TNF RII (TNFRSF1B), TNF RI (TNFRSF1A), TECK (CCL25), TGF beta 1, TIMP-1, TIMP-2, TNF alpha, VEGF-A, XEDAR
Human Obesity Array G1
(AAH-ADI-G1)G-Series Arrays - Semi-Quantitative, Sandwich-Based, Glass Slide Antibody Arrays
Detects 62 Human Adipokines:
4-1BB (TNFRSF9/CD137), ACE-2, Adiponectin (ACRP30), Adipsin (Complement Factor D), AgRP, Angiopoietin-1, Angiopoietin-2, ANGPTL4, CRP (C-Reactive Protein), ENA-78 (CXCL5), Fas (TNFRSF6/Apo-1), FGF-6, Growth Hormone, HCC-4 (CCL16), IFN-gamma, IGFBP-1, IGFBP-2, IGFBP-3, IGF-1, IGF-1 R, IL-1 R4 (ST2), IL-1 R1, IL-10, IL-11, IL-12 p70, IL-1 alpha (IL-1 F1), IL-1 beta (IL-1 F2), IL-6, IL-6 R, IL-8 (CXCL8), Insulin, IP-10 (CXCL10), Leptin R, Leptin, LIF, Lymphotactin (XCL1), MCP-1 (CCL2), MCP-3 (MARC/CCL7), M-CSF, MIF, MIP-1 beta (CCL4), MSP alpha/beta, Osteoprotegerin (TNFRSF11B), Oncostatin M, PAI-1, PARC (CCL18), PDGF-AA, PDGF-AB, PDGF-BB, RANTES (CCL5), Resistin, SAA (Serum Amyloid A), SDF-1 alpha (CXCL12 alpha), TNF RII (TNFRSF1B), TNF RI (TNFRSF1A), TECK (CCL25), TGF beta 1, TIMP-1, TIMP-2, TNF alpha, VEGF-A, XEDAR
Product Features
- Quantitative or Semi-Quantitative level of up to 62 Adipokines are detected simultaneously
- No need to perform individual immunoprecipitations or Western Blot
- Reliable results with wide range of cell lines
- High specificity, sensitivity and reproducibility
- Membrane formats - No special equipment required
- Glass slide formats - Fluorescent laser scanner is needed*
- Many choices: chemiluminescence or fluorescence detection system; Membrane or glass chip
*Click here for a list of compatible laser scanners. Raybiotech now offers free glass slide scanning and data extraction services (click to learn more!).
How It Works
References
- Bauer D., Mazzio E., Soliman K., Taka E., Oriaku E., et al. Diallyl Disulfide Inhibits TNF?-induced CCL2 Release by MDA-MB-231 Cells. ANTICANCER RESEARCH 34: 2763-2770 (2014)
Species: Human
Sample Type: Cells Conditioned Media
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