Obesity Arrays

Obesity and the diseases arising from it (diabetes, cardiovascular disease and cancer) constitute a major health challenge to the industrialized world. In the past decade, it has become apparent that adipose tissue is not an inert fat-storage depot, but a major endocrine organ which secretes numerous soluble factors and regulates many processes related to glucose homeostasis, lipid and protein metabolism, hunger/satiety, inflammatory and immune responses, and vascular function. Collectively, these factors are referred to as adipokines. Some are mainly produced by adipose tissue (e.g., leptin and resistin), while others are classical cytokines such as TNF-α, IL-6, MCP-1, and IL-1, which are also synthesized in other tissues. Understanding adipokine-mediated molecular signaling is critical to understanding and treating the myriad of diseases resulting from obesity.

RayBiotech offers 5 different Obesity Antibody Arrays for detecting up to 62 Adipokines. See the below product listings for more information.

Human Arrays
Product Features
How It Works
References

Human Obesity Arrays

Human Obesity Array Q1

(QAH-ADI-1)

Quantibody Arrays - Quantitative, Sandwich-Based, Glass Slide Antibody Arrays

Detects 10 Human Adipokines:

IGF-1, IL-1 beta (IL-1 F2), IL-6, IL-8 (CXCL8), Insulin, Leptin, MCP-1 (CCL2), PAI-1, Resistin, TNF alpha

Manual Quantibody Overview

Human Obesity Array Q3

(QAH-ADI-3)

Quantibody Arrays - Quantitative, Sandwich-Based, Glass Slide Antibody Arrays

Detects 40 Human Adipokines:

Adiponectin (ACRP30), Adipsin (Complement Factor D), AgRP, ANGPTL4, BDNF, Chemerin, CRP (C-Reactive Protein), Growth Hormone, IFN-gamma, IGFBP-1, IGFBP-2, IGF-1, IL-10, IL-12 p40, IL-12 p70, IL-1 beta (IL-1 F2), IL-1 ra (IL-1 F3), IL-6, IL-8 (CXCL8), Insulin, Leptin, Lipocalin-2 (NGAL), MSP alpha/beta, Osteoprotegerin (TNFRSF11B), PAI-1, PDGF-BB, Pepsinogen 1, Pepsinogen 2, Procalcitonin, Prolactin, RANTES (CCL5), RBP4, Resistin, SAA (Serum Amyloid A), TGF beta 1, Thrombospondin 1, TNF RI (TNFRSF1A), TNF RII (TNFRSF1B), TNF alpha, VEGF-A

Manual Quantibody Overview

Human L182 Array, Membrane

(AAH-BLM-ADI-1)

L-Series Arrays - Semi-quantitative, label-Based, high density antibody arrays

Detects 182 Human Adipokines:

ACE / CD43, ACE-2, ACTH, ADFP, Adiponectin, Adipsin (Factor D), AgRP , AMPKa1 , Amylin, Angiopoietin 1, Angiopoietin 2, Angiotensinogen / Angiotensin II, Ang-like Factor, ANGPTL1, ANGPTL2, ANGPTL3, ANGPTL4 , Apelin Receptor , ApoB, ApoE, Axl, BDNF, bFGF, BMP-2 , BMP-3, BMP-3b / GDF-10, BMP-4 , BMP-5, BMP-6, BMP-7, BMP-8, BMP-15, BMPR-IA / ALK-3, BMPR-IB / ALK-6, BMPR-II, b-NGF, C3a des Arg, CART , CD137 (4-1BB), CD36, Clusterin, CNTF, C-peptide, CRP , Cystatin C, Dtk, EGF, EGFR, ENA-78, Endophin Beta, Epiregulin, E-selectin, ET-1 (Endothelin), FABP4, FAM3B, FAS / Apo-1, FGF-10, FGF-6, FSH , Galectin -1, Growth Hormone (Growth Hormone), Ghrelin, GITR, GITR Ligand, GLP-1 , Glucagon, Glut1, Glut2, Glut3, Glut5, Glutathione peroxidase 1, Glutathione peroxidase 3, GRO alpha, HCC4, HGF, HSD-1, ICAM1, IFN-gamma, IGF-1, ...View all 182 human adipokine proteins

Manual L-Series Overview

Human Obesity Array C1

(AAH-ADI-1)

C-Series Arrays - Semi-Quantitative, Sandwich-Based, Membrane Antibody Arrays

Detects 62 Human Adipokines:

4-1BB (TNFRSF9/CD137), ACE-2, Adiponectin (ACRP30), Adipsin (Complement Factor D), AgRP, Angiopoietin-1, Angiopoietin-2, ANGPTL4, CRP (C-Reactive Protein), ENA-78 (CXCL5), Fas (TNFRSF6/Apo-1), FGF-6, Growth Hormone, HCC-4 (CCL16), IFN-gamma, IGFBP-1, IGFBP-2, IGFBP-3, IGF-1, IGF-1 R, IL-1 R4 (ST2), IL-1 R1, IL-10, IL-11, IL-12 p70, IL-1 alpha (IL-1 F1), IL-1 beta (IL-1 F2), IL-6, IL-6 R, IL-8 (CXCL8), Insulin, IP-10 (CXCL10), Leptin R, Leptin, LIF, Lymphotactin (XCL1), MCP-1 (CCL2), MCP-3 (MARC/CCL7), M-CSF, MIF, MIP-1 beta (CCL4), MSP alpha/beta, Osteoprotegerin (TNFRSF11B), Oncostatin M, PAI-1, PARC (CCL18), PDGF-AA, PDGF-AB, PDGF-BB, RANTES (CCL5), Resistin, SAA (Serum Amyloid A), SDF-1 alpha (CXCL12 alpha), TNF RII (TNFRSF1B), TNF RI (TNFRSF1A), TECK (CCL25), TGF beta 1, TIMP-1, TIMP-2, TNF alpha, VEGF-A, XEDAR

Manual C-Series Overview

Human Obesity Array G1

(AAH-ADI-G1)

G-Series Arrays - Semi-Quantitative, Sandwich-Based, Glass Slide Antibody Arrays

Detects 62 Human Adipokines:

Manual G-Series Overview

Product Features

Quantitative or Semi-Quantitative level of up to 62 Adipokines are detected simultaneously
No need to perform individual immunoprecipitations or Western Blot
Reliable results with wide range of cell lines
High specificity, sensitivity and reproducibility
Membrane formats - No special equipment required
Glass slide formats - Fluorescent laser scanner is needed*
Many choices: chemiluminescence or fluorescence detection system; Membrane or glass chip

*Click here for a list of compatible laser scanners. Raybiotech now offers free glass slide scanning and data extraction services (click to learn more!).