Small Molecules
RayBiotech offers a large catalog of over 8,000 high-quality small molecules to study cell signaling pathways. Small molecules are natural or artificial organic compounds that are < 900 daltons, which bind to and affect the function of specific biological macromolecules. They have wide applications in research, medicine, and farming.
RayBiotech also has small molecule libraries for high throughput screening. These libraries consist of over 2,500 small molecules that target hundreds of proteins in over 20 signaling pathways or research areas. These small molecules, which include inhibitors, antagonists, and agonists, have validated biological and pharmacological activities. To get a quote, contact us at [email protected]
Diagram of the small molecule, imatinib mesylate, binding to its target protein, BCR-ABL. Imatinib mesylate (Gleevec®) is most commonly used to treat Philadelphia chromosome-positive chronic myeloid leukemia (CML).
Applications
- In vitro and vivo experiments
- Understand role of target protein in cell signaling and phenotype
- Identification of enzymatic roles versus structural roles of the target
- Understand relationship between dose-dependent activity and phenotype
Advantages
- Simple to use
- Highly penetrant effects across different cell lines and populations
- Easily combined with other treatments
- Spectrum of phenotypes (dose-dependent)
- Rapid target binding
- Reversible and irreversible binding
