Pathway Analysis

What it is

Pathway analysis identifies the specific protein functions, biological pathways, and physical interactions that are enriched in a particular group. The data are obtained from:

  • GO (Gene Ontology)
  • KEGG (Kyoto Encyclopedia of Genes and Genomes)
  • STRING

When should this service be used?

  • Profiling
  • Sample stratification
  • Biomarker discovery

What you get

Your final report will contain the following information:

  • Description of analysis steps performed
  • Pathway enrichment
    • List of enriched pathways and FDR values
    • List of the proteins, their known functions and processes, and p-values related to their enrichment
    • Enriched biological pathways (see figure)
    • Enriched molecular functions
    • Enriched biological processes
  • Protein interaction mapping
    • List of proteins identified in your study that have known interactions with each other
    • Protein interaction map (see figure)

See Pricing & Packages

KEGG pathway over-representation analysis on differentially-expressed biomarkers (FDR < 0.05)

KEGG pathway over-representation analysis

Protein interaction map

where proteins are represented as nodes and interactions as edges

Protein interaction map