Protein Name & Synonyms:
This PTPLA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human PTPLA.
The protein encoded by this gene contains a characteristic catalytic motif of the protein tyrosine phosphatases (PTPs) family. The PTP motif of this protein has the highly conserved arginine residue replaced by a proline residue; thus it may represent a distinct class of PTPs. Members of the PTP family are known to be signaling molecules that regulate a variety of cellular processes. This gene was preferentially expressed in both adult and fetal heart. A much lower expression level was detected in skeletal and smooth muscle tissues, and no expression was observed in other tissues. The tissue specific expression in the developing and adult heart suggests a role in regulating cardiac development and differentiation.
PTPLA; HACD1; 3-hydroxyacyl-CoA dehydratase 1; Cementum attachment protein; Protein-tyrosine phosphatase-like member A
NCBI Accession #
Other Accession #
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
WB: 1:1000; IHC: 1:10-50
|PTPLA Antibody (N-term) (Cat# 102-12022) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PTPLA antibody detected the PTPLA protein (arrow).|
|PTPLA Antibody (N-term) (Cat# 102-12022)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTPLA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.|
2-8°C (short-term); -20°C (long-term)