AIP, ARA9, FKBP16, FKBP37, SMTPHN, XAP-2, XAP2, AH receptor-interacting protein
Accession Number
O00170
Gene Symbols
AIP
Gene Id
9049
Recommended Applications
Western Blotting,IHC
Purity
Affinity purification
Background
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene.
Dilutions
WB 1:200 - 1:500 IHC 1:50 - 1:100
Format
Calculated MW
37kDa
Observed MW
38kDa
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human AIP (NP_003968.3).
Modification
Unmodified
Storage
-20°C
Images
Western blot analysis of extracts of various cell lines, using AIP antibody (144-09852) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Immunohistochemistry of paraffin-embedded mouse kidney using AIP antibody (144-09852) at dilution of 1:100 (40x lens).
Expiration:
12 months from the date of shipment when stored properly.
