Rabbit anti-ALDH1A2 Antibody

ALDH1A2 Polyclonal Antibody

$200.00
144-07503-50
+

Antigen Information

Accession Number:
  • O94788
Gene ID:
  • 8854
Gene Symbols:
  • ALDH1A2
Protein Name & Synonyms:
ALDH1A2, RALDH(II), RALDH2, RALDH2-T, retinal dehydrogenase 2
Target Species:
  • Human

Antibody Specifications

Applications:
WB,IHC
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal Antibodies
Isotype:
IgG

Background

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

Dilutions

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Format

Calculated MW
46kDa/53kDa/54kDa/56kDa
Observed MW
57kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ALDH1A2 (NP_733797.1).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of various cell lines, using ALDH1A2 antibody (144-07503) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 90s.
Western blot - ALDH1A2 antibody (144-07503)

Immunohistochemistry of paraffin-embedded rat kidney using ALDH1A2 antibody (144-07503) at dilution of 1:100 (40x lens).
Immunohistochemistry - ALDH1A2 antibody (144-07503)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.