Rabbit Anti-ATG3 (N-term)

Rabbit Anti-ATG3 (N-term) Antibody, 400 µl

$408.00  
102-23031
+

Antigen Information

Accession Number:
  • Q0VCL3
  • Q6AZ50
  • Q6GQE7
  • Q9CPX6
  • Q9NT62
Gene ID:
  • 64422
Gene Symbols:
  • ATG3
Protein Name & Synonyms:
Ubiquitin-like-conjugating enzyme ATG3, 632-, Autophagy-related protein 3, APG3-like, hApg3, Protein PC3-96, ATG3, APG3, APG3L

Antibody Specifications

Applications:
WB
Clone:
RB7456
Host Species:
Rabbit
Species Reactivity:
H
Clonality:
Polyclonal
Isotype:
Rabbit Ig

Introduction

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG3L is an E2-like conjugating enzyme facilitating covalent binding of APG8 (MAP1LC3) to phosphatidylethanolamine (PE). APG7 (an E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with APG3. Formation of the PE conjugate is essential for autophagy.

Other Information

Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
35864

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.