Rabbit anti-BCAM Antibody

BCAM Polyclonal Antibody

$200.00  
144-60773-50
+

Antigen Information

Accession Number:
  • P50895
Gene ID:
  • 4059
Gene Symbols:
  • BCAM
Protein Name & Synonyms:
BCAM, AU, CD239, LU, MSK19, basal cell adhesion molecule
Target Species:
  • Human

Antibody Specifications

Applications:
WB
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Mouse
Clonality:
Polyclonal
Isotype:
IgG

Background

This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
67kDa
Observed MW
90kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 352-547 of human BCAM (NP_005572.2).

Modification

Unmodified

Storage

-20°C

Images

Western blot analysis of extracts of mouse lung, using BCAM antibody (144-60773) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 60s.
Western blot - BCAM antibody (144-60773)

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.