Protein Name & Synonyms:
BFSP2, CP47, CP49, CTRCT12, LIFL-L, PHAKOSIN, phakinin
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.
WB 1:500 - 1:2000
Recombinant fusion protein containing a sequence corresponding to amino acids 116-415 of human BFSP2 (NP_003562.1).
Store at -20°. Avoid freeze / thaw cycles.