Protein Name & Synonyms:
CLCN4, CLC4, ClC-4, ClC-4A, MRX15, MRX49, chloride voltage-gated channel 4
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Human, Mouse, Rat
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins.
WB 1:500 - 1:2000
Recombinant fusion protein containing a sequence corresponding to amino acids 600-700 of human CLCN4 (NP_001821.2).
Store at -20°. Avoid freeze / thaw cycles.