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Rabbit anti-CNTFR Antibody

CNTFR pAb

$200.00  
144-62326-50
+

Antigen Information

Accession Number:
  • P26992
Gene ID:
  • 1271
Gene Symbols:
  • CNTFR
Protein Name & Synonyms:
CNTFR, ciliary neurotrophic factor receptor
Target Species:
  • Human

Antibody Specifications

Applications:
WB, IHC
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human, Rat
Isotype:
IgG

Background

This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

Dilutions

WB 1:500 - 1:2000; IHC 1:50 - 1:200

Format

Calculated MW
40kDa
Observed MW
41kDa

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 90-342 of human CNTFR (NP_671693.1).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

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Usage

This product is furnished for LABORATORY RESEARCH USE ONLY.
Not for diagnostic or therapeutic use.