Rabbit anti-CRY2 Antibody

CRY2 pAb
CODE:  144-62731-50

Antigen Information

Accession Number:
  • Q49AN0
Gene ID:
  • 1408
Gene Symbols:
  • CRY2
Protein Name & Synonyms:
CRY2, HCRY2, PHLL2, cryptochrome-2
Target Species:
  • Human

Antibody Specifications

Applications:
WB, IF
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugation/Tag:
Unconjugated
Host Species:
Rabbit
Purity:
Affinity purification
Species Reactivity:
Human
Isotype:
IgG

Background

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene.

Dilutions

WB 1:500 - 1:2000; IF 1:50 - 1:200

Format

Calculated MW
60kDa/66kDa
Observed MW

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 455-614 of human CRY2 (NP_066940.2).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot